Reportedly, seizure susceptibility in the FXS is age-dependent: C57BL/6 Fmr1 KO mice showed higher susceptibility between P15 and P47, while it is between P14 and P94 in FVB Fmr1 KO mice (Musumeci et al., 2000, 2007; Yan et al., 2005). Here, FMR1 is linked to fragile X syndrome.