Apoptotic effects of PK7088 on three gastric cancer cell lines (NUGC-3, NUGC-4 and MKN-1) and two human hepatoblastoma cell lines (HUH-6 and HUH-7) were determined by induction of caspase-3/7 after 6 h PK7088 treatment at different concentrations (Figure 2). Here, CASP3 is linked to hepatoblastoma.