Although not all markers of sensitivity found for AML were also associated with responses in lymphoma or multiple myeloma, we found that the phosphorylation signals of PML p-S506 and MARCKS p-S170 also positively correlate, with viability after treatment with PI-103 in our set of lymphoma and multiple myeloma cells (R = 0.72 and 0.59, respectively) (Additional file 9, Figure S5B). Here, PML is linked to acute myeloid leukemia.