In contrast, it was interesting to observe that phosphorylation sites on two phosphopeptides derived from MARCKS, which are substrates of PKCs (Ref [37]) and which thus provide a measure of PKC activities, correlated (R = 0.74 and 0.78) with the resistance of our AML panel to PI-103 (Figure 7B). This evidence concerns the gene MARCKS and acute myeloid leukemia.