The reported series show that the occurrence of evidence of microangiopathic hemolytic anemia, mild renal failure, severe thrombocytopenia (<25,000 platelets/microliter), and increased liver enzymes with an elevated LDH/GPT ratio in a pregnant woman with fluctuating neurological symptoms should suggest TTP as a first diagnostic hypothesis, rather than other potential microangiopathic conditions such as the HELLP syndrome [2-4]. This evidence concerns the gene GPT and congenital thrombotic thrombocytopenic purpura.