CENPE and neoplasm: For example, KIF2 and KIF15 have been identified as tumor antigens in breast cancer [12], [13]; KIF13A is overexpressed in some retinoblastomas [14]; KIF20A is up-regulated in pancreatic cancer [15]; KIF3 and KIF4 have been identified as tumor suppresser genes in gastric cancer [16], [17]; and the expression of KIF10 is reduced in hepatocellular carcinoma [18].