In particular, IFN-β has been shown to be an effective therapeutic treatment for collagen-induced arthritis (Van Holten et al., 2004; Adriaansen et al., 2006), relapsing-remitting multiple sclerosis (MS) (Weinstock-Guttman et al., 2008) and autoimmune familial Mediterranean fever (Tweezer-Zaks et al., 2008; Guarda et al., 2011). Here, IFNB1 is linked to myeloid sarcoma.