To investigate the relationship between FOXF2 mRNA levels in primary tumors and DFS status in breast cancer patients, Kaplan-Meier survival analysis was used to compare the DFS status of breast cancer patients with tumors of differing FOXF2 mRNA levels, after a follow-up period of 3-year, 5-year, and overall follow-up time. The gene discussed is FOXF2; the disease is breast cancer.