This is the first clinical study to show diminished mRNA expressions of proangiogenic growth factors (PDGFB) and their receptors (VEGFR2, FGFR1, and FGFR2) in gastric ulcer margins of cirrhotic patients, and that these diminished expressions were well correlated with lower platelet count in these patients. This evidence concerns the gene PDGFB and gastric ulcer.