When the top 341 GAPDH positively correlated genes (r greater than or equal to 0.6) identified in the NSCLC dataset were compared with those from the cultured fibroblasts, the up-regulated GAPDH positively correlated genes (including at least 34% of the GACC genes) in both the NSCLC and the fibroblasts cultured in 3% oxygen (low oxygen tension and anti-senescence) were found to be similar (Figure 4). This evidence concerns the gene GAPDH and non-small cell lung carcinoma.