Similar to the results of this study, a previous report has also shown that 17‐ODYA and miconazole did not affect EET and DHET (dihydroxy eicosatrienoic acid) levels in rat tumor tissues.30 It is possible that EETs are produced from an unidentified CYP epoxygenase isoform (not sensitive to the CYP inhibitors used in this study) that is upregulated in coronary ECs, since the 2 known EET‐producing CYP epoxygenases (CYP2C9 and CYP2J2) are inhibited by H2O2,10 the key vasodilator factor in HCAs from patients with CAD. The gene discussed is CYP2J2; the disease is coronary artery disorder.