Genes representative of the B/P and T/NK metagenes were profiled prospectively in a panel of estrogen receptor-positive (ER+), formalin-fixed paraffin-embedded (FFPE) breast tumor sections using the Panomics QuantiGene Plex 2.0 RNA assay system (Affymetrix, Santa Clara, CA, USA). Here, ESR1 is linked to breast neoplasm.