SPP1 and Stroke: Many of these genes have been previously associated with the IR following ABI’s (i.e., TBI, stroke, nerve agent exposure) including CCL13/CCL2, CCL4, CCL6, CCL7, CCR5, CD14, CD44, CDKN1A, CEBPB, CEBPD, CXCL13, CXCL9, CSF1, FOS, HBEGF, HSPA1A/HSPA1B, ICAM1, IER3, IL-1β, IRF1, IRF2, JAK2, LCN2, MMP3, MMP9, MYD88, NF-κB, PSMB8, S100A4, SPP1, STAT3, TLR2, TLR4, and TNFRSF1A [10,13,21,24-34].