The number of hypertension drugs was comparable between senior and nonseniors; however, compared to the nonseniors, seniors used a significantly higher proportion of diuretics (53.8% vs 29.2%, P=.005) and angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers (60.2% vs 35.4%, P=.005). The gene discussed is ACE; the disease is hypertensive disorder.