After miR-449a transfection following irradiation treatment, the altered cell cycle pattern of CL1-0 (Fig. 4D) was shifted to be similar to that of CL1-5 (Fig. 1D), which was identified as a radiosensitive cell line in this lung adenocarcinoma model and also displayed G2/M arrest pattern post irradiation. This evidence concerns the gene COLEC10 and lung adenocarcinoma.