Our results show that lipoxin treatment at the time of infection significantly prolonged survival of both infected Alox5−/− mice (MST 17.5 vs. 3.5 days) and WT mice (MST 20 vs. 5 days) for 15-epi-LXA4-treated and PBS-treated groups, respectively (Figure 5A). The gene discussed is ALOX5; the disease is infection.