SLC5A5 and gastric cancer: The present study was to introduce a noninvasive method for monitoring miRNA-16 in the chemoresistance of gastric cancer through a dual imaging reporter gene system in which human sodium iodide symporter (hNIS) and firefly luciferase (Fluc) genes were linked to a fusion gene for bioluminescence imaging and 99mTc-pertechnetate gamma camera imaging in vivo.