SIRT1 and Alzheimer disease: The values in young controls were between 7.16 and 10.93 ng/μl, in elderly controls 4.41 and 5.96 ng/μl, in MCI patients the concentration were between 3.35 and 3.81 ng/μl and finally in AD patients the concentrations of SIRT1 were in the range of 1.37 and 2.99 ng/μl.