Remarkably, there was a highly significant correlation (Spearman’s rho = 0.95, p<0.001) between BRCA1 and BRCA2 expression in the 19 cell lines (Table 1), suggesting that these genes are co-regulated in HNSCC, similar to what has been shown in mammary epithelial cells [35]. Here, BRCA2 is linked to head and neck squamous cell carcinoma.