Furthermore, there was limited cross-reactivity with the other SSc patients' IgG: some pt4-specific phage clones (pc4.22, pc4.26, pc4.33 and pc4.40) were recognized to a variable extent by anti-Ap1-17 IgG from pt5, pt7 and pt9, while none of the 11 pt14-specific clones reacted with the other patients' anti-Ap1-17 IgG. The gene discussed is ZNF79; the disease is systemic sclerosis.