Point mutations in RAD54A or in its homologue RAD54B in human cells are associated with many types of tumors [20] and the unbalanced expression of RAD54A is associated with cancer progression [21], [22] in malignant cell lines (such as LNCaP, DU-145, PC-3) characterized by non-reciprocal chromosomal translocations [23], [24]. This evidence concerns the gene RAD54L and cancer.