CFHR3 and membranoproliferative glomerulonephritis: Deletions as a result of NAHR lead to the loss of CFHR1, CFHR3 and CFHR4. Deletions within genes, occurring through both NAHR and MMEJ, result in the formation of hybrid genes (CFH/CFHR1, CFHR1/CFH, CFH/CFHR3, CFHR3/CFHR1) associated with diseases such as atypical haemolytic uraemic syndrome (aHUS) and membranoproliferative glomerulonephritis (MPGN) [7]–[9].