In accordance with other recent reports (26), a serum IP-10 level of 400 pg/mL can be considered a reliable marker for the evaluation of the severity of liver disease, which may distinguish patients with expected treatment non-response or relapse after antiviral therapy for hepatitis C.To our knowledge, this is the first study providing data on the baseline characteristics of the HIV-HCV co-infected patients in Romania. This evidence concerns the gene CXCL10 and hepatitis C virus infection.