Among the 24 tumours overexpressing p53 a positive correlation was found between stathmin and p53 (Spearman r = 0.49; 95% C.I. 0.10–0.75 p = 0.01; Fig 8D) and between DNA-PK and p53 (Spearman r = 0.59; 95% C.I. 0.24–0.80 p = 0.002; Fig 8E). This evidence concerns the gene PRKDC and neoplasm.