SPP1 and coronary artery disorder: In summary, we suggested that in asymptomatic patients with coronary artery disease, serum uric acid mildly relates to metabolic factor (type two diabetes mellitus, total cholesterol, and creatinine), bone-related proteins (osteopontin, osteoprotegerin), proinflammatory proteins (hs-C-reactive protein), left ventricular election fraction, and parameters that are attributed to vascular calcification (Agatston score index and coronary artery stenosis of more 50%).