First, to compare the profiles of tumor-infiltrating cytotoxic T lymphocytes between invasive and noninvasive EMPD, we employed immunohistochemical staining for CD8 (Figures 1(a) and 1(b)), granulysin (Figures 1(c) and 1(d)), TIA-1 (Figures 1(e) and 1(f)), and perforin (Figures 1(g) and 1(h)). The gene discussed is PRF1; the disease is neoplasm.