Overexpression of TFEB induced lysosomal exocytosis in a mouse model of multiple sulfatase deficiency (MSD) and in cells derived from the murine models of mucopolysaccharidosis type IIIA (MPS-IIIA), neuronal ceroid lipofuscinoses, and MSD (Medina et al, 2011). The gene discussed is TFEB; the disease is mucosulfatidosis.