CDH1 and breast cancer: Additionally, our finding that the hsa-miR-200 cluster showed lower expression in normal-like/claudin-low breast cancer cell lines fits with the fundamental literature that these miRNAs are indeed involved in EMT, because the majority of the normal-like/claudin-low cell lines lack E-cadherin protein expression, exhibit low claudin expression, and generally display EMT-like features as well as the breast cancer stem cell phenotype (CD44high/CD24low) [50-53].