Similar up- and down- regulated trends with DNA microarray were detected in the genes encoding key molecules implicated in inflammation (e.g. IL-17RA, TLR-2), tumor invasion and metastasis (e.g. MMP25), adhesion (e.g. CD36, VCAM1), extracellular matrix degradation (e.g. TIMP2), cytoskeletal organization (e.g. ACTG2, ACTA2). The gene discussed is MMP25; the disease is neoplasm.