A significant increase in the number of both Annexin V-positive and PI-negative (early apoptosis) and Annexin V- and PI-positive (late apoptosis) ACC-M cells was detected in the pBαbe-SR-IκBα plasmid group with graded doses of irradiation, compared with the 0 Gy group (Fig. 6). The gene discussed is NFKBIA; the disease is adrenal cortex carcinoma.