Moreover, compared with those in the benign tumors, the expression strength of HSP27 was lower in malignant tumor (r=−0.382, pr=0.001), but those of HSP70, HSP86 and HSP84 were higher (r= 0.360, 0.457 and 0.290, respectively; each P<0.01; Fig. 1B). This evidence concerns the gene HSP90AA1 and cancer.