The expression rates of HSP27, HSP60, HSP70, HSP86 and HSP84 were 90.24% (37/41), 70.73% (29/41), 78.05% (32/41), 75.61% (31/41) and 70.73% (29/41) in the benign tumor group, respectively. This evidence concerns the gene HSPD1 and benign neoplasm.