AR and cancer: In the present study, ASC-J9 was combined with specific chemotherapeutic drugs to treat UUTUC cells, indicating that in AR-overexpressing cells, BFTC-pBabeAR1 and BFTC-pBabeAR2, ASC-J9 restored the cyototoxic effect of anti-cancer drugs, revealing that AR plays a significant role in the chemoresistance of UUTUC cells.