STMN1 and cancer: Numerous studies have noted that upregulated expression of stathmin in several types of cancer, including breast (9), colorectal (10), endome-trial (11), head and neck (12), hepatocarcinoma (13), lung (14), ovarian (15) and prostate cancer (16), was correlated with the malignant biological behavior of cancer cells, as well as poor treatment responses to microtubule-targeting drugs (13,17,18).