As demonstrated in Table III, the expression of each IAP group was a significant independent prognostic marker for recurrence-free survival (PcIAP1-N+Survivin-N=0.016; PcIAP1-C+cIAP2+XIAP=0.029; PSurvivin-C+Livin=0.032), in addition to the presence of muscle-invasive disease and high tumor grade. This evidence concerns the gene BIRC5 and neoplasm.