CDH13 and melanoma: It was shown by MTT assays that the proliferation in T-cadherin-transfected B16F10 melanoma cells was markedly lower than either the parental (without transfection) or empty pEGFP-N1 (without T-cadherin gene)-transfected B16F10 cells (P<0.05), while the proliferation in the parental and empty pEGFP-N1-transfected B16F10 cells was similar (P>0.05, Fig. 2E).