BRCA1 and neoplasm: Figs. 3 and 4 illustrate the Kaplan-Meier estimated survival curves for distant metastasis-free survival in patients classified according to the levels of DNA-PKcs and BRCA1 expression in the tumor, respectively (P=0.001, P=0.055, P=0.001). We further performed a Cox regression for multivariate analysis (Table III).