In the present study, we measured the level of pro-inflammatory cytokines, tumor infiltrating granulocytes (TIGs) and tumor-associated macrophages (TAMs), determined the granulocyte/lymphocyte (G/L) ratio and examined the expression of granulocyte colony-stimulating factor (tG-CSF) and macrophage colony-stimulating factor (tM-CSF) in tumor cells to evaluate their role in tumor progression. The gene discussed is CSF3; the disease is neoplasm.