As the majority of lncRNAs share the same biogenesis mechanisms and have a similar structure with mRNAs, including the 5-UTR, ORF and 3-UTR, it is logical to assume that PTCSC3, a lncRNA, may be targeted by certain miRNAs that are upregulated in thyroid cancers. The gene discussed is PTCSC3; the disease is thyroid cancer.