One report suggests that p55α and p50α but not p85α are under transcriptional control of STAT3 [15], and a view of STAT3 expression in the publically available R2 data base containing expression data from a set of 87 neuroblastoma tumors [17], show that STAT3 is significantly lower expressed in stage 4 tumors compared to stage 1 tumors (Additional file 2). The gene discussed is STAT3; the disease is neuroblastoma.