Significant increases in cytoplasmic OCT4 expression were also seen between the breast tumor tissues and the normal resting (P = 0.008 for lactating adenomas; P = 0.019 for lactating carcinoma) and lactating breast tissues (P = 0.008 for lactating adenomas; P = 0.033 for lactating carcinoma), with the highest expression observed in lactating adenomas (Table 3; Figure 4). The gene discussed is POU5F1; the disease is breast neoplasm.