CTCF and neoplasm: In the same vein, CTCF regulates coding mRNAs as well as non-coding RNAs, in the same field of tumor suppression, control of cell cycle and proliferation, including embryonic stem cell differentiation for RNA regulators (Saito and Saito, 2012), which nicely corroborates the way CTCF acts in one case, anticipates it in the second one.