KLK3 and neoplasm: Furthermore, the murine anti-PSA IgG1 (AR47.47) complexed with PSA showed enhanced antigen presentation by human dendritic cells (DC) and induced both CD4 and CD8 T-cell activation [15], suggesting the possibility that this antibody may interact with PSA in the blood of patients redirecting this antigen into APC for antigen processing, presentation, and T-cell activation against the tumor.