ALB and neoplasm: In addition, Desai [32] and Cortes and Saura [33] found that albumin nanoparticles could increase albumin receptor, 60-kDa glycoprotein (gp60)-mediated transcytosis, through microvessel endothelial cells in angiogenic tumor vasculature and targets the albumin-binding protein SPARC, which subsequently increased intratumoral accumulation.