As expected, GLT-1 protein expression in C6 glioma cells was significantly downregulated by DEX treatment, based on Western blotting analysis of whole-cell lysates (24 hours: F1,18 = 12.8; P < 0.01; 48 hours: F1,18 = 5.2; P < 0.05; Figure 5A). The gene discussed is SLC1A2; the disease is glioma.