It has been previously shown that MBA size variation is associated with the severity of chorioamnionitis in a pregnant sheep model of intra-amniotic Ureaplasma infection [28], therefore MBA size variation might influence the interaction of MBA with TLR2/TLR6 heterodimers and thus determine the intensity of the innate immune response and consequently the severity of amniotic fluid infection. This evidence concerns the gene TLR6 and Ureaplasma urethritis.