LEPR and colorectal cancer: In the first stage, the LEPR rs12037879 G/A polymorphism was associated with marginally increased colorectal cancer risk, with ORs of 1.34 (95%CI: 1.01–1.80) and 1.40 (95%CI: 1.06–1.85) for GA vs GG and GA+AA vs GG, respectively.