PTPRC and asthma: To investigate whether reduced Th2 response during OVA/Alum asthma in β5i KO mice is due to impairment in DC maturation, mice were challenged intranasally with a FITC-OVA conjugate and FITC-OVA positive iDCs (F4/80−CD11c+CD11b+Ly6C+B220−, gating strategy in Figure S3) were analyzed on the following day.