Further work shows that purified onfFN, from human hepatoma HUH-7 cells overexpressing the ppGalNAc-T6 gene, but not the non-glycosylated, so called “normal” FN (norFN), induces EMT in human lung cells A549 and NCI-H358 [33]. This evidence concerns the gene FN1 and hepatocellular carcinoma.