SNPs rs1011970 at 9p21/CDKN2A/2B and rs941764 at 14q32/CCDC88C were associated with ER+ breast cancer with ORs (95% CI) 1.27 (1.05–1.54) (P = 0.014) and 1.26 (1.02–1.56) (P = 0.032), respectively. Here, CDKN2A is linked to breast cancer.