Reports on electrotransfer of siRNA to tumors are scarce; so far electrotransfer of siRNAs has been only used for silencing of reporter green fluorescent protein in a stably transfected tumor cells B16F10 and for silencing of vascular endothelial growth factor VEGF and Rho GTPase Rac1 genes [38]–[40]. Here, RAC1 is linked to neoplasm.