IL27RA and infection: Multiple innate MHC-II+ cell populations produced higher amounts of IL-12 in infected WSX-1−/− mice (day 13 of infection) compared with corresponding cells from WT mice, indicating that WSX-1 signalling, directly or indirectly, broadly suppresses the innate compartment during infection; however, CD8+ DCs appear to be the most potent source of IL-12 in infected WSX-1−/− mice (Figure S7A).